| Causes of CS-instability
© Dr. sc. med. Bodo Kuklinski
Foreword
The instability in the cervical spine region has reached pandemic dimensions in Germany and Austria, in fact in all nations of the world with a high level of motorised transport. The reasons for this increase are not only traffic accidents but rather, in the majority, traumatic influences in the use of spare time, in the private sphere at home, while doing sports, during surgical operations under general anaesthesia, but also neurotoxical damages caused by viral infections or neurotoxical exposition to harmful substances such as pollutants. The primary damages come in appearance with a high degree of probability, already during an unnatural child delivery.
The average citizen nowadays suffers mostly from multiple violent influences on the head, neck, shoulders, torso and spinal chord, which cause successively increasing cervical spine instability. These influences begin during the pre-school age and keep on appearing like a chain of events throughout the whole life of an individual. The higher the damages in the cervical spine are, the lower is the threshold of violent influences that can suffice as a last event for the complete deterioration of health. Even single traumatic events can, due to high kinetic energy or by special conditions of influence, cause massive instability.
In the clinical estimation, the “cervical spine – syndrome“ was observed rather narrowly with the accompanying of local pain, hearing and sight instability, as well as nausea. From the point of view of a medical practitioner of inner organs, an initially unstable cervical spine gives rise to chronically functional disturbances which affect all the systems of organs. If the unstable cervical spine is not detected at an early stage as the fundamental cause and maintaining reason for the disturbances and a therapy is not applied, such functional disturbances affecting several organs could develop and reach dimensions which are known as common public illnesses. The illnesses that clinically appear in the foreground can vary according to individual genetic particularities, working conditions, nutritional or living habits. As a rule however, these are mainly multiple system illnesses, known as comorbidities, which comprise the following systems and organs:
The brain, the peripheral and vegetative (autonomous) nervous system
All sense organs
The lungs, heart, organs of the digestive tract
The endocrine and immune systems
The organs of the urogenital tract
The skin
The skeletomuscular system
This is the reason why for example people suffering from sinusitis, tinnitus, visual disorders, headaches, migraine, pain in the joints, muscle aches or lower back pains, exercise-induced asthma, irritated intestine, cardiac arrhythmias, high blood pressure, obesity, diabetes mellitus, chronic tiredness, ADS, ADHS, depressions, losses of memory, allergies, malfunctions of the menstrual cycle, irritable bladder and many more complications visit the appropriate medical practitioners or specialists. The fact that an unstable cervical spine is the principal cause behind all these disorders is not recognised by the medical doctors, let alone by the patients.
On the sub-cellular level the consequences are dramatic. There is a development of NO-induced mitochondrial disorders with a subsequent malfunction of the metabolism and of the energy production, which in turn force the organism to undergo important counter reactions, in order to assure its own survival. Mitochondrial disorders may induce damages to genes in the cell nucleus and in the mitochondria themselves. The latter are inherited with the genetic material of the mother. These disorders are expressed in children in multiple system illnesses with a disorder in the development of the brain (auditory, visual, cognitive, mental, social development) and illnesses of the immune system, manifested in increased rates of atopy. These children with a mitochondrial disadvantage suffer from numerous traumatic influences of the cervical spine as well, which in turn give rise to dramatic multi - system illnesses at a very early age. Vertical research in the archives of medical history (research of medical records of more generations within a family) in Germany and Austria showed, that grandparents, parents, children and grandchildren could be affected from damages in the cervical spine and subsequent illnesses, with the difference, that with every following generation damages are more dramatic and visible at an earlier stage. An alarming snowball effect endangers the health and performance capacity of future generations and consequently the existence of a certain population. Nowadays it is already recognisable, that more and more children and young people cannot cope with the future demands of a competitive society.
It remains to ascertain:
of mental and physical handicaps. The medical corps is helpless by facing these multi-system-affecting illnesses. Physicians and doctors act by focusing on specific organs, because the organic disturbances ought to be visible or measurable. When measurements or visible effects are not detectable, the only abused safe explanation is the psychosomatic factor. Numerous physicians in specialised medical disciplines and sub-disciplines mark their claims on people, for which they are responsible and forbid other colleagues to make an interdisciplinary diagnosis and therapy. An appropriate integrated course of action under consideration of several organs is urgently necessary.
On the grounds of further development in research findings in the natural sciences, physicians neglected the most important instrument of a proper diagnosis – the careful questioning of the former medical history of a patient and its development. They substituted this questioning by diagnosis achieved through laboratory and medical equipment measurements. For severe illnesses this development was beneficial, but for chronic illnesses it failed. In focus is not the person as a whole. Instead, solitary organic symptoms are cured, while the causal mechanisms affect further the multi-organic handicap. As a result a patient suffering from CS damages is a regular visitor of 5 to 10 specialists and that over a period of years, without the specialists being able to eliminate the progress of chronic illnesses. Instead of understanding the fundamental causes of multiple system diseases, modern medicine is on a race with the cost-bearing procedure of a medical approach based on therapy and medication. Intelligent physicians have always sought the “primary disease“. Many diagnoses are in fact one diagnosis. This is what they had been taught.
We presume that the unrecognisable CS-instability is the most important initiator and promoter of a disease affecting several organic systems on a broad basis. We are able to prove this assertion with primary laboratory results.
| Births: |
- caesarean section
- extraction births
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| Household: |
- Fall from a staircase
- Fall from a ladder, a tree, scaffolding, hit while standing up from a bowed position
- Fall from a changing table, a stool, a bunk bed
- Romping around, landing on the chin, the neck, the head,
- on the edge of a bed, on objects etc.
- Hard physical labour (house building, agriculture,
- „sudden stretching“)
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General anaesthesia (with CS-overstretch)
Sudden CS-manipulations („reset of spinal parts“)
| Leisure time: |
- Fall from a tree, a scaffolding, a cliff, the swing, out of the
- Window, in pits and shafts, on the house floor
- Fall by slipping on ice, slippery tiles, in public swimming pools
- Falling on the coccyx, spine, head, back head, chin, shoulders,
- arms, various impacts, impact during bicycle riding, sled-riding,
- ice-skating, roller-blade riding against walls, trees, other persons, impact on pavements
- Head-jump in shallow waters and impact on the head,
- e.g. during children games
- Letting go during riding wheel, falling on stairs, pavement, edges during skate-board riding
- Mountain trekking, down-hill-cycling, unexpected impact on the neck, on the head, hard-hit on the head by a hard ball
- Blows, kicks against the head, especially by persons already in a state of unconsciousness
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| Work: |
“Sudden stretch“during hard labour by storage workers, nursing duties, lifting of heavy weights with an asymmetrical
load
- Falling loads on the head and shoulders
- Kicks, bumps from a bull, a horse, a cow, a ram
- Fall from a tractor, a hay cutter
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| Sports: |
- Team sport and martial arts such as football, handball, volleyball, basketball, water polo, rugby, boxing, wrestling, judo, karate, hockey
- Horse-riding
- Parachuting, water skiing, ski, kite surfing
- Motorsport, moto cross
- Winter sports, downhill skiing, snowboarding, artistic ice-skating, ski-jumping, ice-hockey
- Gymnastics, floor exercises, track and field, high jump, hurdle race, throwing and shoving disciplines
- Mountain climbing
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| Traffic: |
- Being hit by a bicycle, a motorbike, a car
- Car accidents with the parents, as a front seat passenger
- or as a driver
- Impact while cycling against obstacles, open car doors
- Accidents caused by bus, by train
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High velocities, centrifugal forces and gravity release kinetic energy on the CS. When traumatic accidents occur, the outer wounds and eventually a concussion are treated. The CS will be assessed, if examined, by visible, but long ago acquired morphological alterations such as fractures, slipped disc, restrictions of the bone marrow from 1973 (1). The dynamic components, i.e. the high motility as a result of lesions of ligaments, fasciae, muscles and joint capsules remain undetected. However they take place 6 times more often than bone fractures (2).
The result of our research of medical histories was that the most often occurred CS-traumas take place in the house-hold, during leisure time and while doing sport. Following the motto „no risk, no fun“, various sport arts become more and more endangering and bolder. One takes a risk on life and limb.
CS-instabilities arise not only as a result of car accidents (whip-lash syndrome). In Germany, Middle Europe and in the other industrial nations a cascade of CS-traumatic experiences affect people from early childhood. The following example can explain the forces being released on the CS by a single fall from a ladder:
A 75 kg heavy person falls down from a height of 2.6 m with his ladder (arched fall) and hits the hard ground with his head. His head weighs ca. 4.5 kg.
- In order to achieve the energy from a height of 2.6 m on the head, a car must run into a wall with a speed of 105 km/h.
- The force acting on the cross-section of the CS lies by the impact by car around
2.7 kN and by the fall off the ladder around 19.1 kN.
- The deformation distances (crumple zones) are higher in the car. The deformation time is in the case of the car ca. 0,048 sec., in the fall off the ladder up to 0,028 sec.
This means that in the case of a fall off the ladder from a height of 2.6 m 7.1-fold higher forces act on the CS in half as much time. It is well known in the solid state physics that the shorter a force on a material acts the more elastically a material gives way (Hooke’s Region). The faster the impact force is released, the faster gives the material way to the Hooke´s Region. Every karate athlete, woodcutter or boxer takes advantage of this effect. In a similar way act physical forces by a head jump in shallow waters, a salto over the steering wheel or the fall off scaffolding or a bunk bed respectively. The upper CS is the most sensitive, most labile region, because in the end this is the point, where all forces act upon.
Consequences of CS-instability:
As a result of CS-hyperactivity the following symptoms appear:
- Activation of sympathetic nervous system
- C-nerve fibre activations and neurogenous infections
- Functional disorders of brain nerves
- Increase of histamine levels
- Damage of brain and blood-brain barrier cells
- Nitrosative stress
ad 1) Stress of the sympathetic nervous system
Depending on various motions, blood vessels supplying the brain contract and lead to a reduction of blood circulation to the brain with levels up to – 80 % (3). They affect the brain stem, the dorsal hippocampus, the cerebellum and the optical and acoustic centres of the cerebral cortex as well as the inner ear. The consequences are:
- Vegetative disorders (in the brain stem)
- Disturbances in the regulation of temperature and blood pressure,
- Hearing and visual disorders
- Tinnitus
- Disturbances in the functions of cognition, memory and concentration
- Hormonal disorders
- Depression, various forms of psychosis
- Sensitivity to stress, increased sensitivity to light, draught and noise in high frequencies
The nerve cord of the sympathetic nervous system runs through the CS (boarder cord, ganglion) and therefore peripheral organs are exposed to this stress of the sympathetic nervous system. Results of this stress are:
- A higher pulse at rest, attacks of tachycardia and additional cardiac beats that could lead to cardiac arrhythmia
- Immobilisation of the intestine
- Increased spasms of the sphincter muscles for the after and the urinary bladder
- Paleness
- Increased flowing velocity of blood
- Increased blood pressure
The effects for the metabolism are the following:
Deficits on:
B-Vitamins |
ω3-polyene fatty acids |
Vitamin C |
Increase of peroxidation by-products |
zinc, magnesium, potassium |
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Repeated minor blood supply to the brain leads to ischemia. After the new continuation of blood supply free radicals O2 are released, which amplify the oxidation and nitration stress (ONOO°-creation). These metabolites are responsible for damages done to the brain and the cells of the blood-brain barrier but also for the initiation of degenerative or infectious brain and nerve diseases (e.g. MS-multiple sclerosis-, ALS-amorphous lateral sclerosis-, Alzheimer-dementia, Morbus Parkinson, strokes, paralyses). Peripherally many other diseases such as Raynaud-diseases, growth disorders of the nails, fungal infections etc. are found).
Conclusion:
Chronic stress of the sympathetic nervous system is an important promoter of chronic cardiac circulatory diseases.
ad 2) Neurogenous infections
Resting C-nerve fibres without a myelin sheath are activated and create an amplified sense of pain, but also peripheral aseptic infections. Peripherally at the neural endings infectious proteins are released. Thus centres of pain relief in the brain lose their effectiveness (6, 7). As a result there appear arthroses such as Heberden-, Bouchard arthritis of the fingers, shoulder joint arthritis, crucial pain and swellings of the joints, particularly in the morning accompanied by stiff joints, low back pains, and pains in the joints of the hips, knees and ankle.
60 % of the skin nerves consist of C-nerve fibres. If they are stimulated, they give rise to acne, pimples, eczemas, rosacea and psoriasis. After massive CS-traumas symmetrical eczemas on both arms or hands and loss of finger nails can arise as a result.
ad 3) Symptoms of brain nerves
These concern almost all brain nerves from I to XII. In the foreground is the trigeminus (5. brain nerve), because it shows a long attachment area in the CS. Headaches, migraines, projected infections in the maxillary sinuses, tooth roots , but also of arteries (arterial infections) could be the results thereof.
Many brain nerves are interconnected in ganglia, so that several symptoms can arise simultaneously, e. g. visual disorders together with nausea and dizziness (Arteria-basilaris-symptoms!).
Eyes:
- Foggy sight, unfocused sight, unclear round contours in the vision field
- Losses in the vision field
- Dizziness during eye motion
- Eye-ache during concentrated reading, intolerance to bright light
- Reading of lines is complicated
- Dryness of conjunctivae
- Double vision, double contours
- reduced ability of twilight vision
- muscae volitantes (floaters)
Further consequences are damages of the optical nerve, of the retina, glaucoma, early cataract, necessity to bear reading glasses at an early age.
Nose:
- restrained nose-breathing, especially at night, tendency to have paranasal sinusitis and polyps
- Common cold with running nose, nose - bleeding
- Restriction of the olfactory sense, dryness of the mucous membrane
Ears:
- Complicated hearing during background noises, deafness
- Penetrating pain in the inner ear
- Itching, eczemas, infection of the auditory canals
- Extreme sensitivity to noise
- Tinnitus, acute hearing loss
Oral cavity/throat:
- Throat or tooth gum infections
- Complicated tongue articulation
- Loss of the taste sense, irritations
- Sore throat
- Increased sensitivity of the mucous membrane of the mouth
- Bite-wounds during chewing
- Swallowing difficulty up to passage stops and spasms of the oesophagus
Larynx:
- Hoarse, husky voice (especially in the morning)
- Loss of the voice by longer speech or singing
Mastication apparatus:
- Pain in the joints or mastication muscles, asymmetrical opening of the mouth
- Places with missing teeth
- projected infections in the dental roots and the tooth gum
- Parodontosis
Neck, shoulders:
- caused by oblique or slanted position of the head e. g. by lying in the supine position:
- Inability to have a long-lasting sleep
- restless sleep, nightmares
- Attacks with tachycardia, sweating, rise of blood pressure, extra systole
- Morning neck-ache, dazed feeling with a long run-up for the day, lack of appetite for breakfast
- morning pain in the lower spinal region LWS
Irritations of the vagus nerve (Activation, Obstruction)
These express themselves in asthma-like states during night time, the urge to urinate, bradycardia, tachycardia, tendency to have diarrhoea.
ad 4) Increased histamine levels
By almost 50 % of CS-instabilities there is the development of Histadelia (histamine-increase), recognisable on the pathologically high values of free histamine (4). Psychological stress, physical burden and intolerable chemical odours lead to a rapid increase in histamine concentrations.
The effects of histadelia are:
- As a chemical messenger of the nerves histamine activates the brain activity and the memory performance. In the brain, 50 % of the existing histamine is localised in the dorsal hypothalamus and in the mast cells. Histadelia leads to restlessness, irritability, impulsiveness and aggression.
- Opening of the blood-brain barrier
- Rise in the synthesis of NO
- Activation of the neurogenous infection, since mast cells are surrounded by C-nerve fibres in a net form. Their stimulation initiates an increased permeation of arteries with the creation of extravasates (oedemas).
- Spasms of the smooth muscle tissue of the bronchial and intestinal tracts. Intestinal colics
- Attacks of tachycardia
- Oversensitivity against insect stings, histamine –rich or amine-rich foodstuffs
and drinks
- Activation of the Th1 to Th2-Shift with an augmented creation of IgE
- Urticaria (nettle rash) caused by chemical, physical or psychic stress factors
- Cerebral over irritation, increased irritability
- increased release of gastrine and creation of gastric acid salt
ad 5) Damages to the blood –brain barrier
Even light cranial traumas could give rise to an increase of the S-100-blood-brain barrier protein. They indicate remaining cognitive deficits (5). They stay in relationship with increased rates of NO-synthesis. More severe cranial traumas portray a double peak NO-course of synthesis. After a renunciation period, the levels of NO rise again from approximately the 6th day onwards.
The S-100-values show a light increase again rapidly with CS- patients. Vertical shocks (walking on a hard pavement, car-driving), carriage of heavy loads, rotations in the CS-region, but also exposition to xenobiotics give a quick rise to increased levels of S-100. These high levels indicate brain damages. By chronic S-100-high levels, antibodies against S-100 could be formed and eventually trigger neuronal damages. The latter are best indicated by an increase of the neuron specific substance enolase (NSE).
The most severe effect is the trigger of a chronic nitrosative stress.
Bibliography:
- Erdmann, H. (Hrsg.) 1973: Die Schleuderverletzung der Halswirbelsäule (The injury of the cervical spine through skidding). Hippokrates-Verlag Stuttgart
- Saternus, K. S.: Zur Mechanik des Schleudertraumas der Halswirbelsäule(The mechanics of the whip-lash syndrome of the cervical spine). Z. Rechtsmedizin 88 (1982) 1 – 11
- Betz, E.: Physiologie und Pathophysiologie der Gehirndurchblutung (Physiology and pathophysiology of the blood supply in the brain). In: Diethelm, L. et al. (Hrsg.): Handbuch der medizinischen Radiologie. Springer-Verl. 1981
- Kuklinski, B.: Substanz P, neurogene Entzündung und Xenobiotika-Susceptibilität (Substance P, neurogenous infections and susceptibility to xenobiotics). Umwelt Med. Gesellsch. 3 (2003) 196 – 200
- Waterloo, K., T. Ingebrigtsen, B. Remner: Neuropsychological function in patients with increased serum levels of protein S 100 after minor head injury. Acta. Neurochir. 139 (1997) 26 – 31
- Keidel, M., P. Rieschke, P. Stude et al.: Antinociceptive reflex alteration in acute posttraumatic head following whiplash injury. Pain, 92 (2001) 329 – 326
- Ikeda, H., Heinke, B., Ruscheweyh, R., Sandkühler, J.: Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia. Science 299 (2003) 1237 – 1240
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